A new laboratory study suggests a link between a diet high in fat and these conditions based on the infant brain as disorder attention deficit hyperactivity disorder (ADHD) and learning Diet Mouse disabilities who rely on memory.
University of Illinois researchers discovered a high fat diet dopamine metabolism changed rapidly in the brains of mice, causing anxiety behavior and learning deficiencies Diet Mouse.
"Interestingly, when administered methylphenidate (Ritalin), learning and memory are gone," said Gregory Freud, MD, professor of the Faculty of Medicine Diet Mouse.
Freud said the disruption of dopamine signaling in the brain is common to both ADHD and the state are overweight or obese. "And a growing number of metabolites of dopamine is associated with anxiety behavior in children," he added Diet Mouse.
Refunds' team explores possible connections between the recent escalation of childhood obesity and childhood adverse psychological conditions, such as impulsivity, depression and ADHD Diet Mouse.
The researchers examined the short-term effects of high-fat (60 percent calories from fat) compared with a low-fat (10 percent calories from fat) on the behavior of two groups of mice four weeks old. A typical Western diet contains 35-45 percent fat, Diet Mouse he said.
"After only a week of high-fat diet, even before we could see any weight gain, the behavior of the mice in the first group began to change," Diet Mouse he said.
Evidence of anxiety include increasing the wheel holes and therefore becomes a reluctance to explore the open spaces. The mice also developed learning deficits and memory, including decreased ability to negotiate a maze and object recognition impaired Diet Mouse.
Getting the mouse on a high-fat diet restored memory low fat in a week, he said.
Diet Mouse In mice on the high fat diet, object recognition impairment was three weeks after the onset of symptoms.
However, previous studies have shown that brain biochemistry normalized after 10 weeks and the body appears to compensate for the power supply. At this time, brain dopamine returned to normal and the mice became obese and developed Diet Mouse diabetes.
"Although mice born to these anxious behaviors and learning disabilities, the study suggests to me that a diet high in fat can trigger anxiety and memory impairment in a child who is genetically or environment for them," Diet Mouse said .
Because animals are adapted to high-fat fare, scientists have also speculated that the sudden withdrawal fat diet may adversely affect anxiety, Diet Mouse learning and memory.
While researchers expected the high-fat diet to stimulate inflammation, which is associated with obesity, they saw no evidence of an inflammatory response in the brain after one to three weeks on the high Diet Mouse fat diet.
However, found that a high fat diet triggers chemical responses that are similar to those observed in addiction, dopamine, an important chemical in the pleasant experiences the addict, the increase in the Diet Mouse brain.
